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Minimal mutational requirements for conversion of a telomere resolvase into a Cre-like site-specific recombinase.

Hairpin telomere resolvases comprise a family of enzymes that produce the hairpin (hp) telomeres of bacteria and their phages that possess linear chromosomes and plasmids terminated by covalently closed hp telomeres. The hp telomeres overcome the dual issues of end replication and protection faced b...

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Autors principals: Shu Hui Huang, Kerri Kobryn
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2026-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0350834
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