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Mitochondrial sirtuin 4 shapes the intestinal microbiota of Drosophila by controlling lysozyme expression

Abstract Background Sirtuins are deacetylases that are highly conserved throughout the animal kingdom. They act as metabolic sensors that coordinate cellular responses, allowing an adapted response to various stressors. Epithelial cells, especially those of the intestine, are directly exposed to a w...

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Auteurs principaux: Mirjam Knop, Christian Treitz, Stina Bettendorf, Judith Bossen, Jakob von Frieling, Shauni Doms, Abdulgawaad Saboukh, Iris Bruchhaus, Ronald P. Kühnlein, John F. Baines, Andreas Tholey, Thomas Roeder
Format: Artigo
Langue:Inglês
Publié: BMC 2025-06-01
Collection:Animal Microbiome
Accès en ligne:https://doi.org/10.1186/s42523-025-00431-x
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