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Irradiation Decreases the Neuroendocrine Biomarker Pro-Opiomelanocortin in Small Cell Lung Cancer Cells In Vitro and In Vivo.

BACKGROUND:Small cell lung cancer (SCLC) is an extremely aggressive disease, commonly displaying therapy-resistant relapse. We have previously identified neuroendocrine and epithelial phenotypes in SCLC tumours and the neuroendocrine marker, pro-opiomelanocortin (POMC), correlated with worse overall...

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Principais autores: Suzanne L Meredith, Jennifer L Bryant, Muhammad Babur, Philip W Riddell, Roya Behrouzi, Kaye J Williams, Anne White
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4746075?pdf=render
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