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Multiple‐Use Microplate Assay for Submicromolar Ultra High‐Throughput Separation of Amines Based on their Degree of Substitution

Small‐molecule amines, typically studied in their more stable and water‐soluble protonated forms, are of central importance in drug discovery. Their structural diversification often relies on N‐alkylation, yielding mixtures of analogs with varying degrees of substitution‐posing a key challenge for p...

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Principais autores: Panna Vezse, Tünde Tóth, Péter Huszthy, Ádám Golcs
Format: Artigo
Sprog:Inglês
Udgivet: Wiley-VCH 2026-04-01
Serier:ChemistryOpen
Fag:
high‐throughput
library synthesis
microplate
molecular recognition
separation
Online adgang:https://doi.org/10.1002/open.202500491
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