THE ROLE OF RIOCIGUAT IN THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH CONNECTIVE TISSUE DISEASE

Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). Binding NO with sGC - enzyme catalyzes the synthesis of a signal molecule of cyclic guanosine monophosphate (cGMP), which plays an important role in the regulation of processes that affect vascular to...

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Detalhes bibliográficos

Principais autores:	O. Ya. Vasiltseva, K. I. Ivanov, E. A. Devetyarova, O. E. Yakovleva
Formato:	Artigo
Idioma:	Russo
Publicado em:	InterMedservice 2019-12-01
coleção:	Евразийский Кардиологический Журнал
Assuntos:	pulmonary hypertension (ph) pulmonary arterial hypertension (pah) pulmonary arterial hypertension associated with systemic connective tissue diseases (pah ctd) pah-specific therapy riociguat
Acesso em linha:	https://www.heartj.asia/jour/article/view/346
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