Characterization of neuroendocrine cell hyperplasia in autoimmune gastritis: improving H&E-based diagnosis through systematic training

Abstract Background The incidence of autoimmune gastritis (AIG) is low, and our understanding of the proliferation of neuroendocrine cells, specifically enterochromaffin-like (ECL) cells, is insufficient because of the reliance on chromogranin A (CgA) staining for diagnostic assistance. The purpose...

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Ngā kaituhi matua:	Lining Wang, Huizhong Xue, Lu Wang, Shanshan Li, Meng Zhao, Xiaogang Liu
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2026-01-01
Rangatū:	BMC Gastroenterology
Ngā marau:	Autoimmune gastritis Enterochromaffin-like cell hyperplasia Chromogranin A Hematoxylin and eosin-stained Pathologist training Diagnostic accuracy
Urunga tuihono:	https://doi.org/10.1186/s12876-025-04375-z
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