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Clinical response of vedolizumab at week 6 predicted endoscopic remission at week 24 in ulcerative colitis

Abstract Background and Aim Vedolizumab is a humanized monoclonal antibody that selectively inhibits the migration of gut‐homing memory T cells into the intestinal submucosa by antagonizing the interaction of α4β7 integrin with MAdCAM‐1. Vedolizumab is employed for ulcerative colitis with moderate t...

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Principais autores: Daisuke Saito, Minoru Matsuura, Ryo Ozaki, Sotaro Tokunaga, Shintaro Minowa, Tatsuya Mitsui, Miki Miura, Akihito Sakuraba, Mari Hayashida, Jun Miyoshi, Tadakazu Hisamatsu
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2021-09-01
Serier:JGH Open
Fag:
colonoscopy
inflammatory bowel disease
ulcerative colitis
Online adgang:https://doi.org/10.1002/jgh3.12630
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