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RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment

Abstract Background Regulator of G protein signaling 5 (RGS5), as a negative regulator of G protein-coupled receptor (GPCR) signaling, is highly expressed in arterial VSMCs and pericytes, which is involved in VSMC phenotypic heterogeneity and vascular remodeling in tumors. However, its role in norma...

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Hlavní autoři: Peng Kong, Xu Wang, Ya-Kun Gao, Dan-Dan Zhang, Xiao-Fu Huang, Yu Song, Wen-Di Zhang, Rui-Juan Guo, Han Li, Mei Han
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2023-11-01
Edice:Biology Direct
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On-line přístup:https://doi.org/10.1186/s13062-023-00437-y
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