Belatacept and carfilzomib-based treatment for antibody-mediated rejection in a sensitized nonhuman primate kidney transplantation model

IntroductionOne-third of HLA-incompatible kidney transplant recipients experience antibody mediated rejection (AMR) with limited treatment options. This study describes a novel treatment strategy for AMR consisting of proteasome inhibition and costimulation blockade with or without complement inhibi...

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Principais autores:	Robin Schmitz, Miriam Manook, Zachary Fitch, Imran Anwar, Isabel DeLaura, Danae Olaso, Ashley Choi, Janghoon Yoon, Yeeun Bae, Mingqing Song, Alton B. Farris, Jean Kwun, Stuart Knechtle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-09-01
coleção:	Frontiers in Transplantation
Assuntos:	belatacept carfilzomib antibody-mediated rejection allosensitization nonhuman primate
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/frtra.2023.1230393/full
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