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LAMP3 plays an oncogenic role in osteosarcoma cells partially by inhibiting TP53

Abstract Background Osteosarcoma (OS) is a common malignant tumor that predominantly occurs in adolescents. Its most common metastasis is to the lungs. As shown in our earlier study, lysosome-associated membrane glycoprotein 3 (LAMP3) is highly upregulated in metastatic OS. However, its role in the...

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Hlavní autoři: Shaoxian Liu, Junyi Yue, Wei Du, Jian Han, Weidong Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-07-01
Edice:Cellular & Molecular Biology Letters
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On-line přístup:http://link.springer.com/article/10.1186/s11658-018-0099-8
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