The assessment for potential thyroid‐mediated endocrine disruption in amphibians: Clarification on the use of new methods and on the interpretation of changes in thyroid histology

Abstract Amphibians (specifically Xenopus laevis) are used as the model species to assess potential endocrine‐disrupting properties in non‐mammalian species through thyroid modality. The amphibian metamorphosis assay is the most frequently available test. Attempts have been made to modify this proto...

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Главные авторы:	European Food Safety Authority (EFSA), Lisa Baumann, Alice Baynes, Susanne Hougaard Bennekou, Kevin Crofton, Zhichao Dang, Sigmund Degitz, Jean‐Baptiste Fini, Mary Gilbert, Henrik Holbech, Andrea Terron, Majorie Van Duursen, Emily McVey, Maria Arena, Aude Kienzler, Simone Rizzuto, Laura Villamar Bouza, Martin Wilks
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2025-12-01
Серии:	EFSA Journal
Предметы:	amphibians endocrine disruptors histopathology study protocols thyroid
Online-ссылка:	https://doi.org/10.2903/j.efsa.2025.9815
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