Dynamic Boolean modeling of molecular and cellular interactions in psoriasis predicts drug target candidates
Summary: Psoriasis arises from complex interactions between keratinocytes and immune cells, leading to uncontrolled inflammation, immune hyperactivation, and a perturbed keratinocyte life cycle. Despite the availability of drugs for psoriasis management, the disease remains incurable. Treatment resp...
Gardado en:
| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2024-02-01
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| Series: | iScience |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2589004224000804 |
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