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The Functional and Molecular Effects of Doxycycline Treatment on Borrelia burgdorferi Phenotype

Recent studies have shown that Borrelia burgdorferi can form antibiotic-tolerant persisters in the presence of microbiostatic drugs such as doxycycline. Precisely how this occurs is yet unknown. Our goal was to examine gene transcription by B. burgdorferi following doxycycline treatment in an effort...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: John R. Caskey, Nicole R. Hasenkampf, Dale S. Martin, Vladimir N. Chouljenko, Ramesh Subramanian, Mercedes A. Cheslock, Monica E. Embers
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019-04-01
Schriftenreihe:Frontiers in Microbiology
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Online-Zugang:https://www.frontiersin.org/article/10.3389/fmicb.2019.00690/full
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