Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells
Niemann-Pick C1-like 1 protein (NPC1L1) is the putative intestinal sterol transporter and the molecular target of ezetimibe, a potent inhibitor of cholesterol absorption. To address the role of NPC1L1 in cholesterol trafficking in intestine, the regulation of cholesterol trafficking by ezetimibe was...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2007-08-01
|
| Colección: | Journal of Lipid Research |
| Materias: | |
| Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S002222752042509X |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|