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Lithocholic Acid Alleviates Deoxynivalenol-Induced Lethal Cholesterol Metabolic Abnormalities in IPI-2I Cells

Deoxynivalenol (DON) is a secondary metabolite of fungi. Ingestion of feed containing DON causes severe intestinal damage in humans and animals, possibly due to cholesterol-enriched lipid raft abnormalities. Cholic acid (CA) and lithocholic acid (LCA) are metabolites of cholesterol transformation, w...

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Principais autores: Yanwei Li, Fang Gu, Haotian Gu, Ping Hu, Hui-Xin Liu, Demin Cai
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-07-01
Serier:Metabolites
Fag:
lithocholic acid
deoxynivalenol
cholesterol
apoptosis
bile acid
Online adgang:https://www.mdpi.com/2218-1989/12/7/659
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