Telomeric DNA–Promyelocytic Leukemia (TEL–PML) Colocalization as an ALT Proxy in Relation to Metastatic Behavior in Osteosarcoma: A Retrospective Cohort Study

Osteosarcoma is the most common primary bone tumor in children, adolescents, and young adults, and metastasis remains the main determinant for a poor outcome. We conducted an exploratory retrospective cohort study using formalin-fixed, paraffin-embedded tissue from 97 patients with histopathological...

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Bibliografiske detaljer

Principais autores:	Rogelio Frank Jiménez-Ortega, Rosa M. Salgado, Berenice Rivera-Paredez, Nelly Patiño, Tania Hilario-Huerta, Silvia Arenas-Díaz, Rafael Velázquez-Cruz, Alberto Hidalgo-Bravo
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2026-05-01
Serier:	Current Issues in Molecular Biology
Fag:	osteosarcoma telomere maintenance alternative lengthening of telomeres TEL–PML colocalization TERT immunohistochemistry
Online adgang:	https://www.mdpi.com/1467-3045/48/6/553
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