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Covariation of Amino Acid Substitutions in the HIV-1 Envelope Glycoprotein gp120 and the Antisense Protein ASP Associated with Coreceptor Usage

The tropism of the Human Immunodeficiency Virus type 1 (HIV-1) is determined by the use of either or both chemokine coreceptors CCR5 (R5) and CXCR4 (X4) for entry into the target cell. The ability of HIV-1 to bind R5 or X4 is determined primarily by the third variable loop (V3) of the viral envelope...

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Principais autores: Angelo Pavesi, Fabio Romerio
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-02-01
Series:Viruses
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Acceso en liña:https://www.mdpi.com/1999-4915/17/3/323
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