Multiplex screening of 275 plasma protein biomarkers to identify a signature for early detection of colorectal cancer

Blood‐based protein biomarkers may be an attractive option for early detection of colorectal cancer (CRC). Here, we used a two‐stage design to measure 275 protein markers by proximity extension assay (PEA), first in plasma samples of a discovery set consisting of 98 newly diagnosed CRC cases and 100...

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Autori principali:	Megha Bhardwaj, Korbinian Weigl, Kaja Tikk, Axel Benner, Petra Schrotz‐King, Hermann Brenner
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2020-01-01
Serie:	Molecular Oncology
Soggetti:	colorectal cancer diagnostic biomarkers early detection proximity extension assay screening sensitivity and specificity
Accesso online:	https://doi.org/10.1002/1878-0261.12591
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