Multiple Myeloma Cells Alter Adipogenesis, Increase Senescence-Related and Inflammatory Gene Transcript Expression, and Alter Metabolism in Preadipocytes

Within the bone marrow microenvironment, mesenchymal stromal cells (MSCs) are an essential precursor to bone marrow adipocytes and osteoblasts. The balance between this progenitor pool and mature cells (adipocytes and osteoblasts) is often skewed by disease and aging. In multiple myeloma (MM), a can...

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Prif Awduron:	Heather Fairfield, Samantha Costa, Carolyne Falank, Mariah Farrell, Connor S. Murphy, Anastasia D’Amico, Heather Driscoll, Michaela R. Reagan
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2021-02-01
Cyfres:	Frontiers in Oncology
Pynciau:	myeloma bone marrow adipocytes senescence microarray mesenchymal stromal cells (MSCs)
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fonc.2020.584683/full
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