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Integrated sequence-based genomic, transcriptomic, and methylation characterization of the susceptibility to tuberculosis in monozygous twins

Background: Tuberculosis (TB) is a complex disease with a spectrum of outcomes for more than six decades; however, the genomic and epigenetic mechanisms underlying the highly heritable susceptibility to TB remain unclear. Methods: Integrated sequence-based genomic, transcriptomic, and methylation an...

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Principais autores: Zhi Liu, Batu Deligen, Zhiqiang Han, Chaolumen Gerile, An Da
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-06-01
Serier:Heliyon
Fag:
Tuberculosis
Inheritable susceptibility
Genomics
Transcriptomics
Epigenetics
Online adgang:http://www.sciencedirect.com/science/article/pii/S2405844024077430
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