The Minor Allele of rs7574865 in the STAT4 Gene Is Associated with Increased mRNA and Protein Expression.

The T allele of rs7574865 in STAT4 confers risk of developing autoimmune disorders. However, its functional significance remains unclear. Here we analyze how rs7574865 affects the transcription of STAT4 and its protein expression.We studied 201 patients (80% female; median age, 54 years; median dise...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Amalia Lamana, Mercedes López-Santalla, Raquel Castillo-González, Ana María Ortiz, Javier Martín, Rosario García-Vicuña, Isidoro González-Álvaro
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2015-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC4646635?pdf=render
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