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In Search of the Holy Grail: Toward a Unified Hypothesis on Mitochondrial Dysfunction in Age-Related Diseases

Cardiolipin (CL) is a mitochondrial signature phospholipid that plays a pivotal role in mitochondrial dynamics, membrane structure, oxidative phosphorylation, mtDNA bioenergetics, and mitophagy. The depletion or abnormal acyl composition of CL causes mitochondrial dysfunction, which is implicated in...

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Autors principals: Jun Zhang, Yuguang Shi
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-06-01
Col·lecció:Cells
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Accés en línia:https://www.mdpi.com/2073-4409/11/12/1906
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