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Charcoal Hemoperfusion for Methotrexate Toxicity: A Safe and Effective Life-Rescue Alternative When Glucarpidase Is Not Available

Background: High dose methotrexate (HDMTX) is used for the treatment of pediatric hemato-oncological diseases. HDMTX can induce acute kidney injury in cases of delayed elimination. The use of leucovorin remains the most effective rescue action. Further treatment options are of difficult access in th...

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Principais autores: Alejandra Rosales, Alvaro Madrid, Marina Muñoz, Jose Luis Dapena, Gema Ariceta
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021-08-01
Serija:Frontiers in Pediatrics
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Online dostop:https://www.frontiersin.org/articles/10.3389/fped.2021.635152/full
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