Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter

Abstract Capillary endothelial cells of the human blood–brain barrier (BBB) express high levels of P-glycoprotein (P-gp, encoded by ABCB1) and ABCG2 (encoded by ABCG2). However, little information is available regarding ATP-binding cassette transporters expressed at the zebrafish BBB, which has emer...

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Detalhes bibliográficos

Principais autores:	Robert W. Robey, Andrea N. Robinson, Fatima Ali-Rahmani, Lyn M. Huff, Sabrina Lusvarghi, Shahrooz Vahedi, Jordan M. Hotz, Andrew C. Warner, Donna Butcher, Jennifer Matta, Elijah F. Edmondson, Tobie D. Lee, Jacob S. Roth, Olivia W. Lee, Min Shen, Kandice Tanner, Matthew D. Hall, Suresh V. Ambudkar, Michael M. Gottesman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2021-12-01
Colecção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-021-03500-8
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