Efficient CRISPR-Mediated Post-Transcriptional Gene Silencing in a Hyperthermophilic Archaeon Using Multiplexed crRNA Expression

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-mediated RNA degradation is catalyzed by a type III system in the hyperthermophilic archaeon Sulfolobus solfataricus. Earlier work demonstrated that the system can be engineered to target specifically mRNA of an endogenous host repor...

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Bibliografski detalji

Glavni autori:	Ziga Zebec, Isabelle Anna Zink, Melina Kerou, Christa Schleper
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2016-10-01
Serija:	G3: Genes, Genomes, Genetics
Teme:	CRISPR RNA gene silencing hyperthermophile Archaea Sulfolobus
Online pristup:	http://g3journal.org/lookup/doi/10.1534/g3.116.032482
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