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Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani

Widespread resistance towards antimony and reports of relapses following miltefosine treatment has severely affected the management of visceral leishmaniasis (VL) in the Indian subcontinent. Paromomycin (PMM), an aminoglycoside antibiotic, has been licensed for VL treatment in India in 2007. Althoug...

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Библиографические подробности
Главные авторы: Aditya Verma, Vasundhra Bhandari, Deepak Kumar Deep, Shyam Sundar, Jean Claude Dujardin, Ruchi Singh, Poonam Salotra
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2017-12-01
Серии:International Journal for Parasitology: Drugs and Drug Resistance
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2211320717301069
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