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ROS1 kinase inhibition reimagined: identifying repurposed drug via virtual screening and molecular dynamics simulations for cancer therapeutics

Precision medicine has revolutionized modern cancer therapeutic management by targeting specific molecular aberrations responsible for the onset and progression of tumorigenesis. ROS proto-oncogene 1 (ROS1) is a receptor tyrosine kinase (RTK) that can induce tumorigenesis through various signaling p...

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Principais autores: Mohammed Alrouji, Sabina Yasmin, Fahad A Alhumaydhi, Sharaf E. Sharaf, Moyad Shahwan, Anas Shamsi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2024-07-01
Serija:Frontiers in Chemistry
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Online dostop:https://www.frontiersin.org/articles/10.3389/fchem.2024.1392650/full
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