New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A

Introduction: Botulinum neurotoxins (BoNTs) cause botulism and are the most potent natural toxins known. Immunotherapy with neutralizing monoclonal antibodies (MAbs) is considered to be the most effective immediate response to BoNT exposure. Hybridoma technology remains the preferred method for prod...

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Auteurs principaux:	Marina Vladimirovna Silkina, Alena Sergeevna Kartseva, Alena Konstantinovna Riabko, Mariia Aleksandrovna Makarova, Metkhun Madibronovich Rogozin, Yana Olegovna Romanenko, Igor Georgievich Shemyakin, Ivan Alekseevich Dyatlov, Victoria Valerievna Firstova
Format:	Artigo
Langue:	Inglês
Publié:	Tabriz University of Medical Sciences 2024-07-01
Collection:	BioImpacts
Sujets:	botulism botulinum neurotoxin clostridium botulinum snap25 human monoclonal antibody k6h6/b5
Accès en ligne:	https://bi.tbzmed.ac.ir/PDF/bi-14-27680.pdf
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