PPARγ Ameliorates Mycobacterium tuberculosis H37Ra-Induced Foamy Macrophage Formation via the ABCG1-Dependent Cholesterol Efflux Pathway in THP-1 Macrophages

Foamy macrophages are present during the course of Mycobacterium tuberculosis (Mtb) infection and seems to be nutrient-rich reservoir and secure reservoir for the bacilli, which leads to bacterial persistence and infection transmission. Peroxisome proliferator activated receptor γ (PPARγ) is a key t...

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Principais autores:	Yutao Ye, Jun Liu, Yang Guo, Yujie Gao, Jiayue Rao, Rigu Su, Lu Zhang, Zikun Huang, Qing Luo, Junming Li
格式:	Artigo
语言:	Inglês
出版:	Frontiers Media S.A. 2022-03-01
丛编:	Frontiers in Microbiology
主题:	tuberculosis PPARγ foamy macrophage ABCG1 cholesterol efflux
在线阅读:	https://www.frontiersin.org/articles/10.3389/fmicb.2022.829870/full
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