A second gene for peroxisomal HMG-CoA reductase? A genomic reassessment

HMG-CoA reductase (HMG33338) catalyzes the conversion of HMG-CoA to mevalonate, the rate-limiting step of eukaryotic isoprenoid biosynthesis, and is the main target of cholesterol-lowering drugs. The classical form of the enzyme is a transmembrane-protein anchored to the endoplasmic reticulum. Howev...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Rainer Breitling, Skaidrite K. Krisans
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2002-12-01
Цуврал:	Journal of Lipid Research
Нөхцлүүд:	genome duplication HMG-CoA reductase isozymes alternative subcellular localization cholesterol metabolism
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0022227520327280
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!