BRCAness as a Biomarker of Susceptibility to PARP Inhibitors in Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is the most common primary brain cancer. GBMs commonly acquire resistance to standard-of-care therapies. Among the novel means to sensitize GBM to DNA-damaging therapies, a promising strategy is to combine them with inhibitors of the DNA damage repair (DDR) machinery, s...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2021-08-01
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| Schriftenreihe: | Biomolecules |
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| Online-Zugang: | https://www.mdpi.com/2218-273X/11/8/1188 |
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