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The Amyloid Cascade Hypothesis 2.0: Generalization of the Concept

Recently, we proposed the Amyloid Cascade Hypothesis 2.0 (ACH2.0), a reformulation of the ACH. In the former, in contrast to the latter, Alzheimer’s disease (AD) is driven by intraneuronal amyloid-β ( i Aβ) and occurs in two stages. In the first, relatively benign stage, Aβ protein precursor (AβPP)-...

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Principais autores: Vladimir Volloch, Sophia Rits-Volloch
格式: Artigo
语言:Inglês
出版: SAGE Publishing 2023-01-01
丛编:Journal of Alzheimer's Disease Reports
在线阅读:https://doi.org/10.3233/ADR-220079
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