Loss of GLP-2R signaling in Glp2r−/− mice increases the long-term severity of graft versus host disease

Background: Glucagon-like peptide-2 (GLP-2) reduces systemic and gut inflammation while preserving mucosal integrity. Preclinical and clinical reports implicate GLP-2 receptor (GLP-2R) agonism as a potential therapy for graft vs. host disease (GvHD). Methods: Here we assessed whether enhanced vs. lo...

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Egile Nagusiak:	Bernardo Yusta, Chi Kin Wong, Dianne Matthews, Jacqueline A. Koehler, Laurie L. Baggio, Daniel J. Drucker
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2026-01-01
Saila:	Molecular Metabolism
Gaiak:	Intestine Enteroendocrine GLP-2 Barrier function GLP-2 receptor Bacteremia
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2212877825002182
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