Sustained activation of 12/15 lipoxygenase (12/15 LOX) contributes to impaired renal recovery post ischemic injury in male SHR compared to females

Abstract Background Acute kidney injury (AKI) due to ischemia-reperfusion (IR) is a serious and frequent complication in clinical settings, and mortality rates remain high. There are well established sex differences in renal IR, with males exhibiting greater injury following an ischemic insult compa...

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Principais autores:	Riyaz Mohamed, Jennifer C. Sullivan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-12-01
Colecção:	Molecular Medicine
Assuntos:	Acute kidney injury Lipoxygenase Gender Renal recovery Sex difference Ischemia
Acesso em linha:	https://doi.org/10.1186/s10020-023-00762-y
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