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Immediate and long-term electrophysiological biomarkers of antidepressant-like behavioral effects after subanesthetic ketamine and medial prefrontal cortex deep brain stimulation treatment

IntroductionBoth ketamine (KET) and medial prefrontal cortex (mPFC) deep brain stimulation (DBS) are emerging therapies for treatment-resistant depression, yet our understanding of their electrophysiological mechanisms and biomarkers is incomplete. This study investigates aperiodic and periodic spec...

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Principais autores: Matthew Bergosh, Sasha Medvidovic, Nancy Zepeda, Lindsey Crown, Jennifer Ipe, Lauren Debattista, Luis Romero, Eimon Amjadi, Tian Lam, Erik Hakopian, Wooseong Choi, Kevin Wu, Jack Yu Tung Lo, Darrin Jason Lee
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-06-01
Serier:Frontiers in Neuroscience
Fag:
electrophysiology
biomarker
depression
behavior
deep brain stimulation
ketamine
Online adgang:https://www.frontiersin.org/articles/10.3389/fnins.2024.1389096/full
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