Peroxiredoxin 2 regulates DAF-16/FOXO mediated mitochondrial remodelling in response to exercise that is disrupted in ageing

Objectives: A decline in mitochondrial function and increased susceptibility to oxidative stress is a hallmark of ageing. Exercise endogenously generates reactive oxygen species (ROS) in skeletal muscle and promotes mitochondrial remodelling resulting in improved mitochondrial function. It is unclea...

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主要な著者:	Qin Xia, Penglin Li, José C. Casas-Martinez, Antonio Miranda-Vizuete, Emma McDermott, Peter Dockery, Katarzyna Goljanek-Whysall, Brian McDonagh
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2024-10-01
シリーズ:	Molecular Metabolism
主題:	Ageing Peroxiredoxin 2 Exercise C.elegans Mitochondrial ER contact sites DAF-16
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2212877824001340
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