Pharmacokinetics, pharmacodynamics, and safety of verinurad with and without allopurinol in healthy Asian, Chinese, and non‐Asian participants

Abstract Verinurad is a selective inhibitor of uric acid transporter 1 (URAT1). Here, we assessed the safety, pharmacokinetics, and pharmacodynamics of verinurad + allopurinol and verinurad monotherapy in healthy participants. Studies 1 (NCT03836599) and 2 (NCT02608710) were randomized Phase 1 studi...

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Detalhes bibliográficos

Principais autores:	Susanne Johansson, David Han, Thomas Hunt, Karin Björck, Delia Florica, Michael Gillen, Jesse Hall, Fredrik Erlandsson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-06-01
coleção:	Pharmacology Research & Perspectives
Assuntos:	allopurinol pharmacokinetics Phase 1 safety verinurad
Acesso em linha:	https://doi.org/10.1002/prp2.929
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