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An exploratory analysis on diastolic function in the intensive compared with less intensive blood pressure control to prevent adverse cardiac remodelling in children with chronic kidney disease (HOT-KID): a parallel-group, open-label, multicentre, randomised, controlled trialResearch in context

Summary: Background: Relationship between blood pressure (BP) control and left ventricular (LV) diastolic function in children with chronic kidney disease (CKD) is uncertain. The aim of this study is to investigate whether achieving lower BP yields a favourable impact on diastolic function. Methods...

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Bibliografiske detaljer
Principais autores: Haotian Gu, John M. Simpson, Janette Cansick, Eric Finlay, Rodney Gilbert, Andrew Lunn, Heather Maxwell, Henry Morgan, Mohan Shenoy, Rukshana Shroff, Pushpa Subramaniam, Jane Tizard, Yincent Tse, Phil Chowienczyk, Manish D. Sinha, Abdel Douiri, Larissa Kerecuk, Reza Razavi, Poothirikovil Venugopalan, John Simpson, Manish Sinha
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-05-01
Serier:EBioMedicine
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2352396425001355
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