Free energy profiles for unwrapping the outer superhelical turn of nucleosomal DNA.
The eukaryotic genome is packaged into a nucleus in the form of chromatin. The fundamental structural unit of chromatin is a protein-DNA complex, the nucleosome, where 146 or 147 base pairs of DNA wrap 1.75 times around a histone core. To function in cellular processes, however, nucleosomal DNA must...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Public Library of Science (PLoS)
2018-03-01
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| Schriftenreihe: | PLoS Computational Biology |
| Online-Zugang: | https://doi.org/10.1371/journal.pcbi.1006024 |
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