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EphA2 super-enhancer promotes tumor progression by recruiting FOSL2 and TCF7L2 to activate the target gene EphA2

Abstract Super-enhancers or stretch enhancers (SEs) consist of large clusters of active transcription enhancers which promote the expression of critical genes that define cell identity during development and disease. However, the role of many super-enhancers in tumor cells remains unclear. This stud...

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Autors principals: Shuang Cui, Qiong Wu, Ming Liu, Mu Su, ShiYou Liu, Lan Shao, Xiao Han, Hongjuan He
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2021-03-01
Col·lecció:Cell Death and Disease
Accés en línia:https://doi.org/10.1038/s41419-021-03538-6
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