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High expression of Rex-orf-I and HBZ mRNAs and bronchiectasis in lung of HTLV-1A/C infected macaques

Abstract HTLV-1 type-A rarely causes lung disease in humans, whereas HTLV-1 type-C is more frequently associated with respiratory failure and premature death. We investigated the genetic basis of HTLV-1C morbidity by constructing a chimeric HTLV-1A/C oI-L encompassing the highly divergent type C orf...

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Ngā kaituhi matua: Sarkis Sarkis, Anna Gutowska, Mohammad Arif Rahman, Luca Schifanella, Katherine C. Goldfarbmuren, Massimiliano Bissa, Ramona Moles, Christina Ramirez, Elijah F. Edmondson, Andrew Warner, Melvin Doster, Isabela Silva de Castro, Robyn Washington-Parks, Sophia Brown, Joshua Kramer, Matthew W. Breed, Kristin E. Killoran, Yogita Jethmalani, Leonid Serebryannyy, Damian FJ. Purcell, Cynthia A. Pise-Masison, Genoveffa Franchini
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2025-09-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-025-63325-1
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