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Coupling of a Novel TIMP3 Peptide to Carboxypeptidase G2 for Pro-Drug Activation at the Tumour Site

Broad-spectrum cytotoxic drugs have been used in cancer therapy for decades. However, their lack of specificity to cancer cells often results in serious side-effects, limiting efficacy. For this reason, antibodies have been used to attempt to specifically target cytotoxic drugs to tumours. One such...

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Principais autores: Mohammed S. Aldughaim, Fatimah Alsaffar, Michael D. Barker
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2021-01-01
Series:Molecules
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Acceso en liña:https://www.mdpi.com/1420-3049/26/3/625
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