Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving
<p>Abstract</p> <p>Background</p> <p>Several susceptibility genetic variants for autoimmune diseases have been identified. A subset of these polymorphisms displays an opposite risk profile in different autoimmune conditions. This observation open interesting questions on the evolutionary forces shap...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2011-06-01
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| Seria: | BMC Evolutionary Biology |
| Hasła przedmiotowe: | |
| Dostęp online: | http://www.biomedcentral.com/1471-2148/11/171 |
| Etykiety: |
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