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Potential Efficacy of Pegylated Interferon-α and a Nucleos(t)ide Analogue as Combination Therapy for HBeAg-Positive Chronic Hepatitis B

Background/AimsDespite the potent suppression of the hepatitis B virus with modern antiviral agents, only a minority of HBeAg-positive patients achieve hepatitis B e antigen seroconversion. We aimed to explore the potential efficacy of combination therapy consisting of pegylated interferon (p-IFN) a...

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Principais autores: Chung-Il Wi, W. Ray Kim, John B. Gross, Linda M. Stadheim, John J. Poterucha
Format: Artigo
Sprog:Inglês
Udgivet: Gastroenterology Council for Gut and Liver 2016-07-01
Serier:Gut and Liver
Fag:
combination antiviral therapy
hbeag-positive chronic hepatitis b
hbe seroconversion
pegylated interferon
entecavir or tenofovir
Online adgang:http://gutnliver.org/journal/view.html?doi=10.5009/gnl14256
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