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Anti-HIV-1 integrase activity of compounds from Cassia garrettiana heartwood

The ethanol extract of heartwood from Cassia garrettiana had strong anti-HIV-1 integrase (IN) activity with an IC50 value of 3.0 µg/mL. Therefore, its fractions and compounds were investigated for their anti-HIV-1 IN effect using the multiplate integration assay (MIA). From bioassay-guided isolation...

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Hlavní autoři: Kingkan Bunluepuech, Chatchai Wattanapiromsaku, Supinya Tewtrakul
Médium: Artigo
Jazyk:Inglês
Vydáno: Prince of Songkla University 2013-12-01
Edice:Songklanakarin Journal of Science and Technology (SJST)
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On-line přístup:http://rdo.psu.ac.th/sjstweb/journal/35-6/35-6-7.pdf
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