Altered synaptobrevin-II trafficking in neurons expressing a synaptophysin mutation associated with a severe neurodevelopmental disorder

Following exocytosis, synaptic vesicles (SVs) have to be reformed with the correct complement of proteins in the correct stoichiometry to ensure continued neurotransmission. Synaptophysin is a highly abundant, integral SV protein necessary for the efficient retrieval of the SV SNARE protein, synapto...

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Главные авторы:	Callista B. Harper, Grazia M.S. Mancini, Marjon van Slegtenhorst, Michael A. Cousin
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2017-12-01
Серии:	Neurobiology of Disease
Предметы:	Synaptic vesicle Endocytosis Neuron Nerve terminal Synaptophysin Synaptobrevin
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S0969996117302103
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