Therapeutic effects of platelet-derived extracellular vesicles on viral myocarditis correlate with biomolecular content

IntroductionExtracellular vesicles (EVs) can potently inhibit inflammation yet there is a lack of understanding about the impact of donor characteristics on the efficacy of EVs. The goal of this study was to determine whether the sex and age of donor platelet-derived EVs (PEV) affected their ability...

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Autori principali:	Danielle J. Beetler, Presley Giresi, Damian N. Di Florio, Jessica J. Fliess, Elizabeth J. McCabe, Molly M. Watkins, Vivian Xu, Matthew E. Auda, Katelyn A. Bruno, Emily R. Whelan, Stephen P. C. Kocsis, Brandy H. Edenfield, Sierra A. Walker, Logan P. Macomb, Kevin C. Keegan, Angita Jain, Andrea C. Morales-Lara, Isha Chekuri, Anneliese R. Hill, Houssam Farres, Joy Wolfram, Atta Behfar, Paul G. Stalboerger, Andre Terzic, Leslie T. Cooper, DeLisa Fairweather
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-01-01
Serie:	Frontiers in Immunology
Soggetti:	coxsackievirus B3 innate immunity complement TLR4 sex differences microRNA
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1468969/full
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