Functional dichotomy in spinal- vs prefrontal-projecting locus coeruleus modules splits descending noradrenergic analgesia from ascending aversion and anxiety in rats

The locus coeruleus (LC) projects throughout the brain and spinal cord and is the major source of central noradrenaline. It remains unclear whether the LC acts functionally as a single global effector or as discrete modules. Specifically, while spinal-projections from LC neurons can exert analgesic...

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Bibliografische gegevens

Hoofdauteurs:	Stefan Hirschberg, Yong Li, Andrew Randall, Eric J Kremer, Anthony E Pickering
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	eLife Sciences Publications Ltd 2017-10-01
Reeks:	eLife
Onderwerpen:	noradrenaline locus coeruleus pain endogenous analgesia chemogenetics attention
Online toegang:	https://elifesciences.org/articles/29808
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