Nitazoxanide synergizes polymyxin B against Escherichia coli by depleting cellular energy

ABSTRACT The rapid expansion of antibiotic-resistant bacterial diseases is a global burden on public health. It makes sense to repurpose and reposition already-approved medications for use as supplementary agents in synergistic combinations with existing antibiotics. Here, we demonstrate that the an...

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主要な著者:	Xuejia Jiang, Dongliang Chen, Xiaoyang Wang, Chunmei Wang, Haihong Zheng, Wenchong Ye, Wen Zhou, Guoping Liu, Keyu Zhang
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology 2024-08-01
シリーズ:	Microbiology Spectrum
主題:	antibiotic adjuvant nitazoxanide antibiotic resistance gram-negative bacteria polymyxin B
オンライン･アクセス:	https://journals.asm.org/doi/10.1128/spectrum.00191-24
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