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Antimicrobial and Antibiofilm Activity of Auranofin and Its Two Derivatives Bearing Naproxen and Acetylcysteine as Ligands Against Staphylococci

<b>Background/Objectives</b>: The ability of bacteria to form biofilms makes them more tolerant to traditional antibiotics. Given the lack of new antibiotic development, drug repurposing offers a strategy for discovering new treatments. Auranofin (AF), a gold-based compound indicated for the treatme...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Caterina Ferretti, Lorenzo Chiaverini, Noemi Poma, Andrea Dalli, Riccardo Di Leo, Laura Rindi, Alessandro Marrone, Iogann Tolbatov, Diego La Mendola, Arianna Tavanti, Tiziano Marzo, Mariagrazia Di Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-01-01
Schriftenreihe:Antibiotics
Schlagworte:
AMR spread
auranofin
auranofin analogues
naproxen
acetylcysteine
<i>Staphylococcus aureus</i>
Online-Zugang:https://www.mdpi.com/2079-6382/14/2/118
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